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Tatiyana Serebryanskaya


Senior Researcher
PhD (Chemistry)

Department: Laboratory for chemistry of condensed systems
Phone: +375 (17) 209-53-06




  • h-index (Scopus) – 11
  • h-index (Web of Science) – 11
  • h-index (Google scholar) –  11

Subject and Class of Degrees

  • 2011 - PhD in inorganic chemistry (“Synthesis, structure, physico-chemical properties and antitumor activity of platinum(II) and palladium(II) chloride complexes with N-substituted tetrazoles“, supervisor Prof. Dr. Pavel N. Gaponik, Belarusian State University);
  • 2001–2006 -  undergraduate education at the Chemical Faculty of the Belarusian State University;
  • 2006 - BSc (Hons) in organic chemistry, (“Synthesis of the diazene- and triazene-containing bistetrazole ligands and their metallocomplexes“, supervisor Prof. Dr. Pavel N. Gaponik, Belarusian State University);
  • 2006–2009  -  post-graduate education (PhD program) at the Chemical Faculty of the Belarusian State University.


  • 2016 – now  -  senior researcher, Laboratory for condensed systems chemistry, Research Institute for Physical-Chemical Problems, Belarusian State University;
  • 2015 – 2016  -  researcher, Laboratory for condensed systems chemistry, Research Institute for Physical-Chemical Problems, Belarusian State University;
  • 2013 – 2015 - postdoctoral fellow, Department of Physical Organic Chemistry, Institute of Chemistry, Saint Petersburg State University;
  • 2012 – 2013  -  Visiting researcher (postdoctoral fellow), Institute of Pharmaceutical and Medicinal Chemistry, TU Braunschweig, Braunschweig, Germany.

Current research activity

  • Coordination and bioinorganic chemistry, polynitrogen heterocycles, azoles, metal-based drug design.


Saint Petersburg State University postdoctoral fellowship (grant 12.50.1256.2013 "Reactivity of ligands with triple CN bond" with Prof. Dr. Sc. Vadim Yu. Kukushkin, SPSU, Russia);

DAAD scholarship for PhD students and young scientists (PKZ A/11/85889, “Tetrazole based gold complexes as novel class of antiproliferative agents and TrxR inhibitors” with Prof. Dr. Ingo Ott, TU Braunschweig, Germany).


  • Honor Award of Belarusian State University (2018);
  • 63rd Lindau Nobel Laureate Meeting, Lindau, Germany (2013).

List of Selected Publications:

1. Serebryanskaya T.V., Kinzhalov M.A., Bakulev V., Alekseev G., Andreeva A., Gushchin P.V., Protas A.V., Smirnov A.S., Panikorovskii T.L., Lippmann P., Ott I., Verbilo C.M., Zuraev A.V., Bunev A.S., Boyarskiy V.P., Kasyanenko N.A. Water soluble palladium(II) and platinum(II) acyclic diaminocarbene complexes: solution behavior, DNA binding, and antiproliferative activity // New J. Chem. 2020. Iss. 44. P. 5762–5773.

2. Tskhovrebov A.G., Novikov A.S., Odintsova O.V., Mikhaylov V.N., Sorokoumov V.N., Serebryanskaya T.V., Starova G.L. Supramolecular polymers derived from the Pt11 and Pd11 schiff base complexesvia C(sp2)-H ... Hal hydrogen bonding: Combined experimental and theoretical studv // J. Qrganornet. Chem. 2019. Vol. 886. P. 71–75. (lF 2.304).

3. Grigorieva I.M., Serebrynskaya T.V., Grigoriev Y.V., Lyakhov A.S., Ivashkevich L.S., Bogomyakov A.S., Lavrenova L.G., Voitekhovich S.V., Ivashkevich O.A. Transition metal chelatc complexcs with tetrazole derived Mannich basc: Metal dependent architecture and properties // Polyhedron. 2018.  Vol. 151. P. 74–81.

4. Tskhovrebov A.G., Vasileva A.A., Goddard R., Riedel Т., Dyson P.J., Mikhaylov V.N., Serebryanskaya T.V., Sorokoumov V.N. Haukka M. Palladium(n)-Stabilized Pyridine-2-Diazotates: Synthesis, Structural Characterization, and Cytotoxicity Studies // J. Inorg. Chem. 2018. Vol. 57. № 3. P. 930–934.

5. Popova E.A., Serebryanskaya T.V., Selivanov S.I., Haukka M., Panikorovsky T.L., Gurzhiy V.V., Kukushkin, V. Yu. Water-Soluble Platinum(II) Complexes Featuring 2-Alkyl-2H-tetrazol-5-ylacetic Acids: Synthesis, Characterization, and Antiproliferative Activity. European // J. Inorg. Chem. 2016. Vol. 28. P. 4659–4667.

6. Serebryanskaya T.V., .Novikov A.S., Guschin P.V., Haukka M., Asfin R.E., Tolstoy P.M., Kukushkin V.Yu. Identification and H(D)-bond energies of C-H(D)…Cl interactios in cloride-haloalkane clusters: a combined X-ray crystallographic, spectroscopic, and theoretical study // Phys. Chem.Chem. Phys. 2016. Vol. 18. P. 14104-14112.

7. Serebryanskaya T.V., Zolotarev A.A., Ott I. A novel aminotriazole-based NHC complex for the design of gold(I) anti-cancer agents: synthesis and biological evaluation // Med. Chem. Commun. 2015. Vol. 6. P. 1186–1189.

8. Serebryanskaya T.V., Novikov A.S., Gushchin P.V., Zolotarev A.A., Gurzhiy V.V., Kukushkin V.Yu. Coupling of platinated triguanides with platinum activated nitriles as a novel strategy for generation of dimetallic systems // Dalton Trans. 2015. Vol. 44. P. 6003–6011.

9. Serebryanskaya Т.V., Lyakhov A.S., Ivashkevich L.S., Schur J., Frias C., Prokop A., Ott I. Gold(I) thiotetrazolates as thioredoxin reductase inhibitors and antiproliferative agents // Dalton Trans. 2015. Vol. 44. P. 1161–1169.

10. Serebryanskaya Т.V., Yung T., Bogdanov A.A., Shchebet A., Johnsen S.A., Lyakhov A.S., Ivashkevich L.S., Ibrahimava Zh.A., Garbuzenco T.S.,  Kolesnikova T.S., Melnova N.I.,  Gaponik P.N., Ivashkevich O.A. Synthesis, Characterization and Biological Evaluation of New Tetrazole-based Platinum(II) and Palladium(II) Chlorido Complexes – Potent Cisplatin Analogues and Their  Trans Isomers // J. Inorg. Biochem. 2013. Vol. 120. P. 44–53.

11. Ivashkevich L.S., Lyakhov A.S., Serebryanskaya Т.V., Gaponik P.N., Ivashkevich O.A. An X-ray powder study of the structure and microstructure of trans-dichloridobis(1,5-diamino-1H-tetrazole-κN4)palladium(II) // Z. Kristallogr. 2012. Vol. 22. P. 702–709.

12. Ivashkevich L.S., Serebryanskaya Т.V., Lyakhov A.S., Gaponik P.N. An X-ray powder diffraction study of cis-dichloridobis(2-methyl-2H-tetrazol-5-amine-κN4)platinum(II), a tetrazole-containing analogue of cisplati // Acta Cryst. 2011. Vol. C67. P. m195–m198.

13. Serebryanskaya Т.V.,  Matulis Vadim E., Lyakhov A.S., Voitekhovich S.V., Gaponik P.N., Ivashkevich O.A. N-Substituted Bis(tetrazol-5-yl)diazenes: Synthesis, Spectra, X-ray Molecular and Crystal Structures, and Quantum-chemical DFT Calculations // Heteroatom Chemistry. 2010. Vol. 21. P. 24–35.

14. Serebryanskaya Т.V., Ivashkevich L.S., Gaponik P.N., Lyakhov A.S., Ivashkevich O.A. 1,3-Bis(2-alkyltetrazol-5-yl)triazenes and their Fe(II), Co(II) and Ni(II) complexes: Synthesis, spectroscopy, and thermal properties. Crystal structure of Fe(II) and Co(II) 1,3-bis(2-methyltetrazol-5-yl)triazenide complexes // Polyhedron. 2010. Vol. 29. P. 2844–2850.

15. Voitekhovich S.V., Serebryanskaya Т.V., Gaponik P.N., Lyakhov A.S., Ivashkevich L.S.,  Ivashkevich O.A. Preparation and characterization of the first coordination compounds of tetrazol-2-ylacetic acid // Inorg. Chem. Comm. 2010. Vol.13. P. 949–951.